変異解析手法をもちいた各種分析論文例

【タイトル要約】
全ゲノム関連解析による平均血小板容量に関わる3つの遺伝子座の同定

Genomu-wide Association Study Identifies Three Loci Associate with Mean Platelet Volume

Christa Meisinger,^1,3,14 Holger Prokisch,^2,4,14 Christian Gieger,^1,5 Nicole Soranzo,^6,7 Divya Mehta,² Dieter Rosskopf,⁸ Peter Lichtner,² Norman Klopp,¹ Jonathan Stephens,¹² Nicholas A. Watkins,¹² Panos Deloukas,⁶ Andreas Greinacher,⁹ Wolfgang Koenig,¹³Matthias Nauck,¹⁰ Christian Rimmbach,⁸ Henry Völzke,¹¹ Annette Peters,¹Thomas Illig,¹Willem H. Ouwehand,^6,12 Thomas Meitinger,^2,4 H.-Erich Wichmann,^1,5 and Angela DÖring^1,*

¹Institute of Epidemiology, ²Institute of Human Genetics, Helmholtz Zentrum München, Gerrman Research Center for Environmental Heaalth. 85764 Neuherberg, Germany; ³Central Hospital of Augsburg, MONICA/KORA Myocardial Infraction R3gistry, 86156 Augsburg, Germany; ⁴Institute of Human Genetics, Technical University, 81765 Munich, Germany; ⁵Institute of Medical Informatics, Biometry and Epidemiology, Ludwig-Maximilians-Universität,81377 Munich, Germany; ⁶Wellcome Trust Sanger Institute, Hunxton, Camridge CB10 1SA, UK; ⁷ King’s College London, Twin Genetic Epidemiology Unit, London SE1 7EH, ⁸Department of Pharmacology, Center for Pharmacology and Eperimental Therapeutics, ⁹Institute of Immunology and Transfusion Medicine, ¹⁰Institute for Clinical Chemistry and Laboratory Medicine, ¹¹Institute for Community Medicine, Ernst-Moritz-Arndt University, 17487 Greifswald, Germany; ¹²Department of Haematology, University of Cambridgeand National Health Service Blood and Transplant(NHSBT), Cambridge CB2 OPT, UK; ¹³University of Ulm Medical Center, Department of Internal Medicine-ⅡCardiology, Ulm 89081, Germany ¹⁴ These authors contributed equally to this work ^*
Correspondence : doering@helmholtz-muenchen.de DOI 10.1016/j.a.jhg.2008.1.015. ©2009 by The American Society of Human Genetics. All rights reserved.